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GEF-H1 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501561341
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Catalog No. Quantity
50-156-1341 100 μL
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Catalog No. 50-156-1341 Supplier Bethyl Laboratories, Inc Supplier No. A301928A
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections. Based on 100% sequence identity, this antibody is predicted to react with Pig

GEF-H1 activates Rho GTPases by promoting the exchange of GDP and GTP. Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. GEF-H1 may be involved in epithelial barrier permeability, cell motility and polarization, dendritic spine morphology, antigen presentation, leukemic cell differentiation, cell cycle regulation, innate immune response, and cancer. Alternatively spliced transcript variants encoding different isoforms have been identified.

Specifications

Antigen GEF-H1
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene ARHGEF2
Gene Accession No. Q92974
Gene Alias AA408978, GEF, GEF-H1, GEFH1, LFP40, Lbcl1, Lfc, P40, mKIAA0651
Gene Symbols ARHGEF2
Host Species Rabbit
Immunogen Between 625 and 675
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9181
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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