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Tocris Bioscience™ Geldanamycin
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Catalog No. 13681R
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Quantity:
1 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Selective Hsp90 inhibitor

Selectively inhibits heat shock protein 90 (Hsp90). Binds to the ATP site of Hsp90 (Kd = 1.2 μM) and inhibits its chaperone activity. Consequently inhibits activities of oncogenic kinases (e.g. src, Raf), p53 and steroid receptors. Demonstrates antiproliferative effect on breast cancer stem-like cells.

Specifications

CAS 30562-34-6
Assay Percent Range >98%
Quantity 1 mg
Solubility Soluble to 10 mM in DMSO
Molecular Formula C29H40N2O9
Formula Weight 560.64g/mol
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