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Tocris Bioscience™ Geldanamycin
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Catalog No. 13681R
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13-681-R 1 mg
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Catalog No. 13-681-R Supplier Tocris Bioscience™ Supplier No. 1368/1
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Description

Selective Hsp90 inhibitor

Selectively inhibits heat shock protein 90 (Hsp90). Binds to the ATP site of Hsp90 (Kd = 1.2 μM) and inhibits its chaperone activity. Consequently inhibits activities of oncogenic kinases (e.g. src, Raf), p53 and steroid receptors. Demonstrates antiproliferative effect on breast cancer stem-like cells.

Specifications

CAS 30562-34-6
Assay Percent Range >98%
Quantity 1 mg
Solubility Soluble to 10 mM in DMSO
Molecular Formula C29H40N2O9
Formula Weight 560.64g/mol
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