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  5. Tocris Bioscience™ Gemcitabine hydrochloride

Tocris Bioscience™ Gemcitabine hydrochloride
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Catalog No. 325950
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Catalog No. Quantity
32-595-0 50 mg
32-591-0 10 mg
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Catalog No. 32-595-0 Supplier Tocris Bioscience™ Supplier No. 3259/50
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Description

DNA synthesis inhibitor

Deoxycytidine analog that inhibits DNA synthesis. Metabolized to form gemcitabine triphosphate (dFdCTP) and gemcitabine diphosphate (dFdCDP). dFdCTD inhibits ribonucleotide reductase causing a reduction in cellular nucleotides. dFdCTP is incorporated in DNA resulting in DNA strand termination. Displays antitumor activity in vitro and in vivo.

Chemical Identifiers

CAS 122111-03-9
Molecular Formula C9H12ClF2N3O4

Specifications

Quantity 50 mg
Formula Weight 299.66
Purity >99%
Molecular Weight (g/mol) 299.659
Chemical Name or Material Gemcitabine hydrochloride

Safety and Handling

Recommended Storage Desiccate at +4°C
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