Gemin 1/SMA Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-1477	100 μL

Catalog No. 50-198-1477 Supplier Bioss Supplier No. BS11561R

Description

Rabbit Polyclonal Antibody

The SMN1 gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. The telomeric and centromeric copies of this gene are nearly identical and encode the same protein - survival motor neuron protein. The SMN complex plays a catalyst role in the assemble of small nuclear ribonucleoproteins, the building blocks of the spliceosome. Mutations in the SMN1 gene are known to cause spinal muscular atrophy 1/2.

Specifications

• Antigen: Gemin 1/SMA
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: SMN1
• Gene Accession No.: Q16637
• Gene Alias: BCD541; Component of gems 1; GEMIN1; Gemin-1; SMA; SMA@; SMA1; SMA2; SMA3; SMA4; SMN; SMN1; SMN2; SMNC; SMNT; survival motor neuron 1 protein; Survival motor neuron protein; survival of motor neuron 1, telomeric; T-BCD541; TDRD16A; tudor domain containing 16A
• Gene Symbols: SMN1
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human Gemin 1.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 6606
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG