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Invitrogen™ Gemin 3 Polyclonal Antibody
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Catalog No. PIPA5120950
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100 μL
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PIPA5120950 100 μL
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Catalog No. PIPA5120950 Supplier Invitrogen™ Supplier No. PA5120950
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Description

Rabbit Polyclonal Antibody

Positive test controls include: MCF7, ES-2, 293T, HepG2, HeLa, Mouse spleen, Rat testis, Mouse ovary. The target is usually found in the following locations: Cytoplasm, Nucleus, gem. Immunogen sequence: VQVPAPEPTP GPVRILRTAQ DLSSPRTRTG DVLLAEPADF ESLLLSRPVL EGLRAAGFER PSPVQLKAIP LGRCGLDLIV QAKSGTGKTC VFSTIALDSL VLENLSTQIL ILAPTREIAV QIHSVITAIG IKMEGLECHV FIGGTPLSQD KTRLKKCHIA VGSPGRIKQL IELDYLNPGS IRLFILDEAD KLLEEGSFQE QINWIYSSLP ASKQMLAVSA TYPEFLANAL TKYMRDPTFV RLNSSDPSLI GLKQYY.

Gemin 3 is a member of the DEAD box protein family which are characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD) and are putative RNA helicases. DEAD box proteins such as Gemin 3 are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of DEAD box family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. Gemin 3 has an ATPase activity and a component of the survival of motor neurons (SMN) complex. The Gemin 3 protein may play a catalytic role in the function of the SMN complex on RNPs. Diseases associated with Gemin 3 protein dysfunction include spinal muscular dystrophy and muscular atrophy.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Gemin 3
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.04 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Ddx20
Gene Accession No. Q9JJY4, Q9UHI6
Gene Alias component of gems 3; DDX 20; DDX20; DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; DEAD box protein 20; DEAD box protein DP 103; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 20; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 20, 103kD; DEAD/H BOX 20; DEAD-box helicase 20; DEAD-box protein DP103; DKFZP434H052; DP 103; Dp103; GEMIN3; Gemin-3; I79_021005; probable ATP-dependent RNA helicase DDX20; putative ATP-dependent RNA helicase DDX20; regulator of steroidogenic factor 1; ROSF-1; SMN-interacting protein
Gene Symbols Ddx20
Host Species Rabbit
Immunogen Recombinant protein (or fragment)
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11218, 53975, 84473
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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