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Gemin 3/SMA Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501981479
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50-198-1479 100 μL
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Catalog No. 50-198-1479 Supplier Bioss Supplier No. BS11563R
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Description

Rabbit Polyclonal Antibody

Gemin 3 is a member of the DEAD box protein family which are characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD) and are putative RNA helicases. DEAD box proteins such as Gemin 3 are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of DEAD box family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. Gemin 3 has an ATPase activity and a component of the survival of motor neurons (SMN) complex. The Gemin 3 protein may play a catalytic role in the function of the SMN complex on RNPs. Diseases associated with Gemin 3 protein dysfunction include spinal muscular dystrophy and muscular atrophy.

Specifications

Antigen Gemin 3/SMA
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Ddx20
Gene Accession No. Q9UHI6
Gene Alias BOS_3153; Component of gems 3; DDX 20; DDX20; DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; DEAD box protein 20; DEAD box protein DP 103; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 20; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 20, 103kD; DEAD/H BOX 20; DEAD-box helicase 20; DEAD-box protein DP103; DKFZP434H052; DP 103; Dp103; GEMIN3; Gemin-3; I79_021005; Probable ATP-dependent RNA helicase DDX20; putative ATP-dependent RNA helicase DDX20; Regulator of steroidogenic factor 1; ROSF-1; SMN-interacting protein
Gene Symbols Ddx20
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human Gemin 3.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11218
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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