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Geminin Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501558829
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50-155-8829 100 μL
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Catalog No. 50-155-8829 Supplier Bethyl Laboratories, Inc Supplier No. A300934A
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

The DNA replication (origin) licensing system is necessary for duplicating the genome in each cell cycle. Geminin is a protein that prevents DNA replication by blocking the MCM complex incorporation into prereplication complex (pre-RC). It is absent during G1 phase and accumulates during S, G2, and M phases of mitosis. It is then degraded during the metaphase-anaphase trasition allowing replication to occur during subsequent cycles. Geminin has also been implicated in maintaining integrity of the male germline genome.

Specifications

Antigen Geminin
Applications Immunohistochemistry, Immunoprecipitation
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene GMNN
Gene Accession No. O75496
Gene Alias Gem, geminin
Gene Symbols GMNN
Host Species Rabbit
Immunogen Between 50 and 100
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51053
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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