GEP100/IQSEC1 Rabbit anti-Human, Polyclonal, Bioss

Rabbit Polyclonal Antibody

Supplier:  Bioss BS13960R

Catalog No. 50-198-3169

Description

ADP ribosylation factors (Arfs) are small GTP-binding proteins known for their role in vesicular transport, where they nucleate the assembly of coat protein complexes at sites of carrier vesicle formation. IQSEC1 (GEP100/BRAG2), a guanine nucleotide exchange protein for ARF6, belongs to the BRAG family and contains one IQ domain, one PH domain and one SEC7 domain. As a known activator of ARF6, IQSEC1 regulates cell surface levels of Beta1 integrin and its knockdown blocked tumour metastasis. IQSEC1 links EGFR signaling to ARF6 activation and may contribute to the cancer metastasis and malignancy.

Specifications

• Antigen: GEP100/IQSEC1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: IQSEC1
• Gene Alias: ADP-ribosylation factors guanine nucleotide-exchange protein 100; ADP-ribosylation factors guanine nucleotide-exchange protein 2; ARFGEP100; ARF-GEP100; AW561907; BC026481; BRAG2; brefeldin A-resistant ARF-GEF2; Brefeldin-resistant Arf-GEF 2 protein; cI-43; D6Ertd349e; GEP100; IQ motif and Sec7 domain 1; IQ motif and SEC7 domain-containing protein 1; Iqsec1; Kiaa0763
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 9922
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 μg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene Accession No.: Q6DN90
• Gene Symbols: IQSEC1
• Immunogen: KLH conjugated synthetic peptide derived from human GEP100.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG