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Invitrogen™ Gephyrin Polyclonal Antibody
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Catalog No. PIPA529036
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100 μL
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PIPA529036 100 μL
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Catalog No. PIPA529036 Supplier Invitrogen™ Supplier No. PA529036
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: NIH-3T3, JC, U87-MG, SK-N-SH, IMR-32, SK-N-AS, mouse brain, rat brain. Predicted reactivity: Mouse (100%), Rat (100%), Xenopus laevis (92%), Pig (100%), Chicken (100%), Rhesus Monkey (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Gephyrin is a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described; however, the full-length nature of all transcript variants is not currently known.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Gephyrin
Applications Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.59 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Gphn
Gene Accession No. Q03555, Q8BUV3, Q9NQX3
Gene Alias 5730552E08Rik; AI662856; BC027112; C230040D23; Domain E; Domain G; EGK_18299; Geph; gephyrin; gephyrin isoform; Gph; GPHN; GPHRYN; HKPX1; KIAA1385; MOCODC; Molybdopterin adenylyltransferase; Molybdopterin molybdenumtransferase; MPT adenylyltransferase; MPT Mo-transferase; Putative glycine receptor-tubulin linker protein
Gene Symbols Gphn
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human Gephyrin. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10243, 268566, 64845
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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