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Invitrogen™ Gephyrin Polyclonal Antibody
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Catalog No. PIPA555157
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100 μL
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PIPA555157 100 μL
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Catalog No. PIPA555157 Supplier Invitrogen™ Supplier No. PA555157
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: SRCSSKENIL RASHSAVDIT KVARRHRMSP FPLTSMDKAF ITVLEMTPVL GTEIINYRDG MGRVLAQDVY AKDNLPPFPA SVKDGYAVRA ADGPGDRFII GESQAGEQPT QTVMPGQVMR VTTGAPIPCG ADAVVQVEDT Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

Gephyrin is a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described; however, the full-length nature of all transcript variants is not currently known.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Gephyrin
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Gphn
Gene Accession No. Q9NQX3
Gene Alias 5730552E08Rik; AI662856; BC027112; C230040D23; Domain E; Domain G; EGK_18299; Geph; gephyrin; gephyrin isoform; Gph; GPHN; GPHRYN; HKPX1; KIAA1385; MOCODC; Molybdopterin adenylyltransferase; Molybdopterin molybdenumtransferase; MPT adenylyltransferase; MPT Mo-transferase; Putative glycine receptor-tubulin linker protein
Gene Symbols Gphn
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human Gephyrin. Recombinant protein control fragment (Product #RP-89068).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10243
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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