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Invitrogen™ GFAP Monoclonal Antibody (5C10)
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Catalog No. PIMA547443
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Quantity:
100 μL
500 μL
Catalog No. Quantity
PIMA547443 100 μL
PIMA547344 500 μL
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Catalog No. PIMA547443

Supplier: Invitrogen™ MA547443

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Mouse Monoclonal Antibody

GFAP Monoclonal Antibody for Western Blot, ICC/IF, IHC (P)

GFAP (Glial fibrillary acidic protein) is a member of the class III intermediate filament protein family. GFAP is heavily and specifically expressed in astrocytes and certain astroglia of the central nervous system, in satellite cells of peripheral ganglia, and in non-myelinating Schwann cells of peripheral nerves. In addition, neural stem cells strongly express GFAP. Antibodies to GFAP are very useful as markers of astrocytic cells. In addition, many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP. GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes. GFAP is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing of the GFAP gene results in multiple transcript variants encoding distinct isoforms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GFAP
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 5C10
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 5mM sodium azide
Gene GFAP
Gene Accession No. P03995, P14136, P47819, Q28115
Gene Alias 6330404F12Rik; 65 kDa glutamic acid decarboxylase; AI836096; ALXDRD; Astrocyte or Intermediate Filament Protein; cb345; class III intermediate filament protein; etID36982.3; FLJ45472; GAD(65); Gad2; Gad-2; GAD65; GAD-65; GFAP; GFAP epsilon; gfap protein; gfapl; glial fibrillary acidic protein; Glial Fibrillary Acidic Protein (GFAP); glial fibrillary acidic protein alpha; glutamate decarboxylase 2; Glutamate decarboxylase 65 kDa isoform; glutamic acid decarboxylase 2; I79_011607; intermediate filament; intermediate filament protein; intermediate filament protein; GFAP; Unknown (protein for MGC:139638); wu:fb34h11; wu:fk42c12; xx:af506734; zgc:110485; zGFAP; intermediate filament protein; zrf-1 antigen
Gene Symbols GFAP
Host Species Mouse
Immunogen Purified porcine spinal cord GFAP.
Purification Method Protein A/G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100033970, 14580, 24387, 2670, 281189, 396562
Target Species Human, Mouse, Rat, Bovine, Pig, Horse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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WARNING: Cancer - www.P65Warnings.ca.gov
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