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Description
This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq]
Specifications
Specifications
| Antigen | GFAP |
| Applications | Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot |
| Classification | Monoclonal |
| Clone | 183CT3.1.5 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against human GFAP. |
| Dilution | Immunohistochemistry (1:50-1:100) Immunofluorescence (1:10-1:50) Western Blot (1:100-1:500) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS (0.09% sodium azide) |
| Gene Alias | FLJ45472 |
| Gene Symbols | GFAP |
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