GFAP Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-0136	100 μL

Catalog No. 50-198-0136 Supplier Bioss Supplier No. BS0199R

Description

Rabbit Polyclonal Antibody

GFAP (Glial fibrillary acidic protein) is a member of the class III intermediate filament protein family. GFAP is heavily and specifically expressed in astrocytes and certain astroglia of the central nervous system, in satellite cells of peripheral ganglia, and in non-myelinating Schwann cells of peripheral nerves. In addition, neural stem cells strongly express GFAP. Antibodies to GFAP are very useful as markers of astrocytic cells. In addition, many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP. GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes. GFAP is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing of the GFAP gene results in multiple transcript variants encoding distinct isoforms.

Specifications

• Antigen: GFAP
• Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: GFAP
• Gene Accession No.: P14136
• Gene Alias: AI836096; ALXDRD; BOS_19250; cb345; class III intermediate filament protein; etID36982.3; FLJ45472; GFAP; GFAP epsilon; gfap protein; gfapl; Glial fibrillary acidic protein; glial fibrillary acidic protein alpha; I79_011607; intermediate filament; intermediate filament protein; intermediate filament protein; GFAP; wu:fb34h11; wu:fk42c12; xx:af506734; zgc:110485; zGFAP; intermediate filament protein; zrf-1 antigen
• Gene Symbols: GFAP
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human GFAP.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2670
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG