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Invitrogen™ GFI1 Polyclonal Antibody
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Catalog No. PIPA523495
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100 μg
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Catalog No. Quantity
PIPA523495 100 μg
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Catalog No. PIPA523495 Supplier Invitrogen™ Supplier No. PA523495
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Description

Rabbit Polyclonal Antibody

GFI1 Polyclonal Antibody for Western Blot, IHC (P)

GFI1 is a nuclear zinc finger (ZF) transcriptional repressor that plays an important role in hematopoiesis and inner ear development, and has been implicated in lymphomagenesis. The Gfi1 protein expression is regulated by the ubiquitin-proteasome system. It is reported that ubiquitin ligase Triad1 interacts with the DNA-binding domain of Gfi-1. Gfi-1 represses transcription by directly binding to the consensus DNA sequence in the promoters of its target genes. Deficiency of Gfi-1 causes neutropenia and an accumulation of granulomonocytic precursor cells that is reminiscent of a myelodysplastic syndrome in mice.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GFI1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene GFI1
Gene Accession No. P70338, Q07120, Q99684
Gene Alias AW495828; FLJ94509; Gfi1; GFI-1; GFI1A; growth factor independence-1; growth factor independent 1; growth factor independent 1 transcription repressor; growth factor independent 1 transcriptional repressor; growth factor independent protein 1; Growth factor independent-1; Pal1; Pal-1; SCN2; Zinc finger protein 163; zinc finger protein Gfi-1; ZNF163
Gene Symbols GFI1
Host Species Rabbit
Immunogen A portion of amino acid 280-330 of human Zinc finger protein Gfi-1.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100139952, 14581, 24388, 2672, 429088
Target Species Human, Mouse, Rat, Bovine, Chicken
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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