Invitrogen™ GFM2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA585482

Catalog No. PIPA585482

Description

Keep as concentrated solution. Predicted reactivity: Mouse (88%), Rat (87%), Rhesus Monkey (98%), Bovine (91%). Positive Control: 293T, A431, HeLa, HepG2, Neuro 2A, C8D30. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

GFM2 is involved in mitochondrial translation, which is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. In Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. This gene encodes one of mitochondrial translation elongation factors. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known. Alternative splicing results in at least three transcript variants encoding distinct isoforms.

Specifications

• Antigen: GFM2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Gfm2
• Gene Alias: 6530419G12Rik; A930009M04Rik; EFG2; EF-G2mt; EF-G2mt {ECO:0000255; Elongation factor G 2, mitochondrial; elongation factor G 2, mitochondrial {ECO:0000255; Elongation factor G2; G elongation factor; G elongation factor mitochondrial 2; G elongation factor, mitochondrial 2; GFM2; HAMAP-Rule:MF_03059}; hEFG2; mEF-G 2; mEF-G 2 {ECO:0000255; mitochondrial elongation factor G2; mitochondrial ribosome recycling factor 2; MRRF2; MST027; MSTP027; RGD1309854; ribosome-releasing factor 2, mitochondrial; ribosome-releasing factor 2, mitochondrial {ECO:0000255; RRF2; RRF2mt; RRF2mt {ECO:0000255
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 320806, 84340
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: Q8R2Q4, Q969S9
• Gene Symbols: Gfm2
• Immunogen: Recombinant protein encompassing a sequence within the center region of human GFM2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov