GFR alpha-1 Polyclonal Antibody, Invitrogen™

Catalog No.	Quantity
PIPA132476	100 μg

Catalog No. PIPA132476

Supplier: Thermo Scientific PA132476

Description

Rabbit Polyclonal Antibody

PA1-32476 detects GFR alpha 1 from human, rat, mouse samples. PA1-32476 has been successfully used in Western blot applications. The PA1-32476 immunogen is: Synthetic peptide: TALRVKNKPLGPAG, corresponding to amino acids 369-382 of Human GFR alpha 1.

Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Multiple alternatively spliced transcript variants have been described for this gene.

Specifications

• Antigen: GFR alpha-1
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Gene: GFRA1
• Gene Accession No.: P56159, P97785, Q62997
• Gene Alias: DKFZp313E1012, DKFZp686J0156, FLJ10561, FLJ31546, GDNFR, GDNFRA, GFR-ALPHA-1, MGC23045, RET1L, RETL1, TRNR1
• Gene Symbols: GFRA1
• Host Species: Rabbit
• Immunogen: synthetic peptide TALRVKNKPLGPAG, corresponding to amino acids 369-382 of Human GFR alpha 1.
• Purification Method: IgG fraction
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 14585, 25454, 2674
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG