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Invitrogen™ GFR alpha-2 Polyclonal Antibody
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Catalog No. PIPA547608
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100 μg
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Catalog No. Quantity
PIPA547608 100 μg
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Catalog No. PIPA547608 Supplier Invitrogen™ Supplier No. PA547608
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Description

Goat Polyclonal Antibody

In direct ELISAs and Western blots, less than 5% cross-reactivity with recombinant human GFR alpha -3 is observed. Reconstitute at 0.2 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.

GFRa-2 binds NTN and mediates activation of RET receptor tyrosine kinase by both NTN and GDNF. Thus, NTN, GFRa-2, and the Ret PTK form a complex to transduce NTN signal and to mediate NTN function.
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Specifications

Antigen GFR alpha-2
Applications Immunohistochemistry (Frozen), Neutralization, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene GFRA2
Gene Accession No. O00451, O08842
Gene Alias GDNF family receptor alpha 2; GDNF family receptor alpha-2; GDNF re; GDNF receptor alpha-2; GDNF receptor beta; GDNFR-alpha-2; Gdnfrb; GDNFR-beta; Gfra2; GFR-alpha 2; GFR-alpha-2; glial cell line derived neurotrophic factor family receptor alpha 2; glial cell line derived neurotrophic factor receptor, beta; HpV18gp1; neurturin receptor alpha; NRTNR-alpha; NTNRA; NTNR-alpha; PI-linked cell-surface accessory protein; RET ligand 2; RETL2; TGF-beta-related neurotrophic factor receptor 2; TRN receptor, GPI-anchored; TRNR2; tyrosine kinase receptor ligand 2
Gene Symbols GFRA2
Host Species Goat
Immunogen Mouse myeloma cell line NS0-derived recombinant mouse GFR alpha-2/GDNF R alpha-2 Ser22-Ser441.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14586, 2675
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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