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Invitrogen™ GFRAL Polyclonal Antibody
Sheep Polyclonal Antibody
Supplier: Invitrogen™ PA547769
Description
In direct ELISA, less than 1% cross-reactivity with recombinant mouse (rm) GFR alpha -3 and rmGFR alpha -4 is observed. Reconstitute at 0.2 mg/mL in sterile PBS.
Brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses (PubMed:28953886, PubMed:28846097, PubMed:28846098, PubMed:28846099). Upon interaction with its ligand, GDF15, interacts with RET and induces cellular signaling through activation of MAPK- and AKT- signaling pathways. [UniProt].
Specifications
GFRAL | |
Polyclonal | |
Unconjugated | |
GFRAL | |
AY457637; bA360D14.1; C6orf144; GDNF family receptor alpha like; GDNF family receptor alpha-like; GDNF receptor alpha-like; GFRAL; Gral; IVFI9356; RGD1565220; UNQ9356; UNQ9356/PRO34128 | |
Sheep | |
Antigen affinity chromatography | |
RUO | |
404194 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Lyophilized |
Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot | |
0.2 mg/mL | |
PBS with 5% trehalose and No Preservative | |
Q6SJE0 | |
GFRAL | |
CHO-derived recombinant mouse GFR alpha-like isoform A Gln20-Gly349. | |
100 μg | |
Primary | |
Mouse | |
Antibody | |
IgG |
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