Invitrogen™ GFRAL Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5107133

Catalog No. PIPA5107133

Description

Sequence homology: Cow: 85%; Human: 100%; Pig: 77%; Rabbit: 92%.

Brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses (PubMed:28953886, PubMed:28846097, PubMed:28846098, PubMed:28846099). Upon interaction with its ligand, GDF15, interacts with RET and induces cellular signaling through activation of MAPK- and AKT- signaling pathways. [UniProt].

Specifications

• Antigen: GFRAL
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GFRAL
• Gene Alias: AY457637; bA360D14.1; C6orf144; GDNF family receptor alpha like; GDNF family receptor alpha-like; GDNF receptor alpha-like; GFRAL; Gral; IVFI9356; RGD1565220; UNQ9356; UNQ9356/PRO34128
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 389400
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide; pH 7.4
• Gene Accession No.: Q6UXV0
• Gene Symbols: GFRAL
• Immunogen: Synthetic peptide directed towards the N-terminal region of Human GFRAL.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG