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Invitrogen™ GGA2 Polyclonal Antibody
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Catalog No. PIPA588267
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100 μL
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PIPA588267 100 μL
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Catalog No. PIPA588267 Supplier Invitrogen™ Supplier No. PA588267
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MAATAVAAAV AGTESAQGPP GPAASLELWL NKATDPSMSE QDWSAIQNFC EQVNTDPNGP THAPWLLAHK IQSPQEKEAL YALTVLEMCM NHCGEKFHSE VAKFRFLNEL IKVLSPKYLG SWATGKVKGR VIEILFSWTV WFPEDIKIRD AYQMLKKQGI IKQDPKLPVD KILPPPSPWP KSSIFDADEE KSKLLTRLLK SNHPEDLQAA NRLIKNLVKE EQEKSEKVSK RVSAVEEVRS HVKVLQEMLS MYRRPGQAPP DQEALQVVYE RCEKLRPTLF RLASDTTDDD DALAEILQAN; Positive Samples: HepG2, Raji, MCF7, THP-1, 22Rv1, Mouse brain, Mouse kidney; Cellular Location: Endosome membrane, Golgi apparatus, Peripheral membrane protein, trans-Golgi network membrane.

This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. This family member may play a significant role in cargo molecules regulation and clathrin-coated vesicle assembly.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GGA2
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.44 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene GGA2
Gene Accession No. Q6P5E6, Q9UJY4
Gene Alias 1200007E24Rik; ADP-ribosylation factor binding protein 2; ADP-ribosylation factor-binding protein GGA2; gam; Gamma-adaptin-related protein 2; Gga2; golgi associated, gamma adaptin ear containing, ARF binding protein 2; golgi-associated, gamma adaptin ear containing, ARF binding protein 2; golgi-localized, gamma ear-containing, ARF-binding protein 2; Kiaa1080; mKIAA1080; VEAR; VHS domain and ear domain of gamma-adaptin; VHS domain and ear domain-containing protein
Gene Symbols GGA2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human GGA2 (NP_0558591).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23062, 74105
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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