Invitrogen™ GGA2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA588267

Catalog No. PIPA588267

Description

Immunogen sequence: MAATAVAAAV AGTESAQGPP GPAASLELWL NKATDPSMSE QDWSAIQNFC EQVNTDPNGP THAPWLLAHK IQSPQEKEAL YALTVLEMCM NHCGEKFHSE VAKFRFLNEL IKVLSPKYLG SWATGKVKGR VIEILFSWTV WFPEDIKIRD AYQMLKKQGI IKQDPKLPVD KILPPPSPWP KSSIFDADEE KSKLLTRLLK SNHPEDLQAA NRLIKNLVKE EQEKSEKVSK RVSAVEEVRS HVKVLQEMLS MYRRPGQAPP DQEALQVVYE RCEKLRPTLF RLASDTTDDD DALAEILQAN; Positive Samples: HepG2, Raji, MCF7, THP-1, 22Rv1, Mouse brain, Mouse kidney; Cellular Location: Endosome membrane, Golgi apparatus, Peripheral membrane protein, trans-Golgi network membrane.

This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. This family member may play a significant role in cargo molecules regulation and clathrin-coated vesicle assembly.

Specifications

• Antigen: GGA2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GGA2
• Gene Alias: 1200007E24Rik; ADP-ribosylation factor binding protein 2; ADP-ribosylation factor-binding protein GGA2; gam; Gamma-adaptin-related protein 2; Gga2; golgi associated, gamma adaptin ear containing, ARF binding protein 2; golgi-associated, gamma adaptin ear containing, ARF binding protein 2; golgi-localized, gamma ear-containing, ARF-binding protein 2; Kiaa1080; mKIAA1080; VEAR; VHS domain and ear domain of gamma-adaptin; VHS domain and ear domain-containing protein
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23062, 74105
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 0.44 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q6P5E6, Q9UJY4
• Gene Symbols: GGA2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human GGA2 (NP_0558591).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG