GGPS1 Mouse anti-Human, Clone: OTI3F9, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA525243
DescriptionGGPS1 (geranylgeranyl diphosphate synthase 1), also known as GGPPS, GGPPSase (geranylgeranyl pyrophosphate synthetase) or GGPPS1, is a member of the FPP/GGPP synthetase family of trans-prenyltransferases. Predomitly expressed in testis, heart and skeletal muscle, GGPS1 localizes to the cytoplasm and catalyzes the formation of geranylgeranyl pyrophosphate (GGPP), a precursor of geranylgeranylated proteins and carotenoids. GGPP is a major isoprenoid responsible for the C20-prenylation of proteins and the regulation of the nuclear hormone receptor LXRalpha. More specifically, GGPS1 functions as an oligomeric molecule and mediates the condensation of farnesyl diphosphate (FPP) with isopentenyl diphosphate to yield GGPP. GGPS1 contains five amino acid motifs that are conserved in trans-prenyltransferases and three potential N-glycosylation sites.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|Geranylgeranyl pyrophosphate synthase; GGPP synthase; GGPPSase; (2E,6E)-farnesyl diphosphate synthase; Dimethylallyltranstransferase; Farnesyl diphosphate synthase; Farnesyltranstransferase; Geranylgeranyl diphosphate synthase; Geranyltranstransferase; GGPS1|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|Full length human recombit protein of GGPS1 produced in HEK293T cell|
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