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GGPS1 Mouse anti-Human, Clone: OTI3F9, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA525243

Catalog No. PIMA525243


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Description

Description

GGPS1 (geranylgeranyl diphosphate synthase 1), also known as GGPPS, GGPPSase (geranylgeranyl pyrophosphate synthetase) or GGPPS1, is a member of the FPP/GGPP synthetase family of trans-prenyltransferases. Predomitly expressed in testis, heart and skeletal muscle, GGPS1 localizes to the cytoplasm and catalyzes the formation of geranylgeranyl pyrophosphate (GGPP), a precursor of geranylgeranylated proteins and carotenoids. GGPP is a major isoprenoid responsible for the C20-prenylation of proteins and the regulation of the nuclear hormone receptor LXRalpha. More specifically, GGPS1 functions as an oligomeric molecule and mediates the condensation of farnesyl diphosphate (FPP) with isopentenyl diphosphate to yield GGPP. GGPS1 contains five amino acid motifs that are conserved in trans-prenyltransferases and three potential N-glycosylation sites.
Specifications

Specifications

GGPS1
Monoclonal
0.81 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
O95749
Geranylgeranyl pyrophosphate synthase; GGPP synthase; GGPPSase; (2E,6E)-farnesyl diphosphate synthase; Dimethylallyltranstransferase; Farnesyl diphosphate synthase; Farnesyltranstransferase; Geranylgeranyl diphosphate synthase; Geranyltranstransferase; GGPS1
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
9453
Immunohistochemistry (Paraffin), Western Blot
OTI3F9
Unconjugated
GGPS1
Liquid
GGPS1
Full length human recombit protein of GGPS1 produced in HEK293T cell
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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