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Tocris Bioscience™ GGTI 298
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Catalog No. 24301
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24-301 1 mg
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Catalog No. 24-301 Supplier Tocris Bioscience™ Supplier No. 2430/1
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Description

Geranylgeranyltransferase I (GGTase I) inhibitor

CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor. Strongly inhibits the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras (IC50 values are 3 and > 10 μM respectively). Causes G0-G1 cell cycle block and apoptosis in A549 cells and inhibits cell invasion and migration in COLO 320CM cells.

Chemical Identifiers

CAS 1217457-86-7
Molecular Formula C29H34F3N3O5S

Specifications

Quantity 1 mg
Formula Weight 593.66
Purity >95%
Molecular Weight (g/mol) 593.662
Chemical Name or Material GGTI 298

Safety and Handling

Recommended Storage Store at -20°C
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