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Tocris Bioscience™ GGTI 298

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Quantity:
1 mg
Description
CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor. Strongly inhibits the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras (IC50 values are 3 and > 10 μM respectively). Causes G0-G1 cell cycle block and apoptosis in A549 cells and inhibits cell invasion and migration in COLO 320CM cells.
Specifications
Specifications
Quantity | 1 mg |
Formula Weight | 593.66 |
Purity | >95% |
Molecular Weight (g/mol) | 593.662 |
Chemical Name or Material | GGTI 298 |
Safety and Handling
Recommended Storage | Store at -20°C |
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