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GGTI 298, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

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Quantity:
1mg
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1217457-86-7
C29H34F3N3O5S
593.662
WALKWJPZELDSKT-UFABNHQSSA-N
ggti 298,ggti298 trifluoroacetate,ggti 298 tfa salt,ggti-298 tfa salt,ggti 298 tfa,ggti 298 trifluoroacetate salt hydrate,tfa,ggti 298 trifluoroacetate salt hydrate hplc , film,n-4-2-r-amino-3-mercaptopropyl amino-2-naphthylbenzoyl leucine methyl ester trifluoroacetate salt hydrate,n-4-2 r-amino-3-mercaptopropyl amino-2-1-naphthalenyl benzoyl-l-leucine methyl ester trifluoroacetate salt
16078971
methyl (2S)-2-[[4-[[(2R)-2-amino-3-sulfanylpropyl]amino]-2-naphthalen-1-ylbenzoyl]amino]-4-methylpentanoate;2,2,2-trifluoroacetic acid
CC(C)CC(C(=O)OC)NC(=O)C1=C(C=C(C=C1)NCC(CS)N)C2=CC=CC3=CC=CC=C32.C(=O)(C(F)(F)F)O
This item is not returnable. View return policy
1217457-86-7
C29H34F3N3O5S
593.662
WALKWJPZELDSKT-UFABNHQSSA-N
ggti 298,ggti298 trifluoroacetate,ggti 298 tfa salt,ggti-298 tfa salt,ggti 298 tfa,ggti 298 trifluoroacetate salt hydrate,tfa,ggti 298 trifluoroacetate salt hydrate hplc , film,n-4-2-r-amino-3-mercaptopropyl amino-2-naphthylbenzoyl leucine methyl ester trifluoroacetate salt hydrate,n-4-2 r-amino-3-mercaptopropyl amino-2-1-naphthalenyl benzoyl-l-leucine methyl ester trifluoroacetate salt
16078971
methyl (2S)-2-[[4-[[(2R)-2-amino-3-sulfanylpropyl]amino]-2-naphthalen-1-ylbenzoyl]amino]-4-methylpentanoate;2,2,2-trifluoroacetic acid
CC(C)CC(C(=O)OC)NC(=O)C1=C(C=C(C=C1)NCC(CS)N)C2=CC=CC3=CC=CC=C32.C(=O)(C(F)(F)F)O

Description

Geranylgeranyltransferase I (GGTase I) inhibitor

CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor. Strongly inhibits the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras (IC 50 values are 3 and > 10 μM respectively). Causes G 0 -G 1 cell cycle block and apoptosis in A549 cells and inhibits cell invasion and migration in COLO 320CM cells.

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Formula Weight 593.66
Percent Purity >95%
Quantity 1mg
Chemical Name or Material GGTI 298

Safety and Handling

Recommended Storage : Store at -20°C