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Tocris Bioscience™ GI 254023X
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Catalog No. 39951
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39-951 1 mg
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Catalog No. 39-951 Supplier Tocris Bioscience™ Supplier No. 3995/1
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Description

Selective ADAM10 metalloprotease inhibitor

Selective ADAM10 metalloprotease inhibitor; displays over 100-fold higher potency at ADAM10 compared to ADAM17. Blocks constitutive release of IL-6R, CX3CL1 and CXCL16 in cell-based cleavage experiments. Inhibits calcium ionophore-induced betacellulin shedding in IMPE cells. Prevents E-cadherin cleavage in A549 cells. Inhibits ADAM10 mediated neuronal outgrowth of dorsal root ganglion neurons in vitro.

Chemical Identifiers

CAS 260264-93-5
Molecular Formula C21H33N3O4

Specifications

Quantity 1 mg
Formula Weight 391.5
Purity >98%
Molecular Weight (g/mol) 391.51
Chemical Name or Material GI 254023X

Safety and Handling

Recommended Storage Store at -20°C
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