Invitrogen™ GIPR Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5118866

Catalog No. PIPA5118866

Description

Antibody detects endogenous levels of total GIPR.

GIPR encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes.

Specifications

• Antigen: GIPR
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GIPR
• Gene Alias: gastric inhibitory peptide receptor; gastric inhibitory polypeptide receptor; GIP receptor; Gippr; Gipr; GIP-R; Glucose-dependent insulinotropic polypeptide receptor; Gm1081; Gm160; PGQTL2; RATGIPPR
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 25024, 2696, 381853
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P43219, P48546, Q0P543
• Gene Symbols: GIPR
• Immunogen: A synthesized peptide derived from human GIPR(Accession P48546), corresponding to amino acid residues A96-S146.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG