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Invitrogen™ GIT1 Monoclonal Antibody (N39B/8), APC
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Catalog No. PIMA545565
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100 μg
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Catalog No. Quantity
PIMA545565 100 μg
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Catalog No. PIMA545565 Supplier Invitrogen™ Supplier No. MA545565
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Description

Mouse Monoclonal Antibody

1 μg/mL of MA5-45565 was sufficient for detection of GIT1 in 10 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 90kDa. Does not cross-react with GIT2. This antibody was formerly sold as clone S39B-8.

GIT1 is a GTPase-activating protein for the ADP ribosylation factor family. It may serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. It increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GIT1
Applications Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone N39B/8
Concentration 1 mg/mL
Conjugate APC
Formulation 2.48mM MES, 95.64mM phosphate with 0.5M EDTA and no preservative; pH 7.4
Gene GIT1
Gene Accession No. Q68FF6, Q9Y2X7, Q9Z272
Gene Alias ARF GAP GIT1; ARF GTPase-activating protein GIT1; CAT1; CAT-1; cool-associated and tyrosine-phosphorylated protein 1; G protein-coupled receptor kinase interacting ArfGAP 1; G protein-coupled receptor kinase interactor 1; G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein; G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein (GIT1); G protein-coupled receptor kinase-interactor 1; GIT ArfGAP 1; Git1; GRK-interacting protein 1; I79_013368; p95Cat
Gene Symbols GIT1
Host Species Mouse
Immunogen Fusion protein amino acids 375-770 (C-terminus) of rat GIT1.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 216963, 28964, 83709
Target Species Human, Mouse, Rat
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG1
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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