Invitrogen™ GIT1 Monoclonal Antibody (N39B/8), FITC

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA545566

Catalog No. PIMA545566

Description

1 μg/mL of MA5-45566 was sufficient for detection of GIT1 in 10 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 90kDa. Does not cross-react with GIT2. This antibody was formerly sold as clone S39B-8.

GIT1 is a GTPase-activating protein for the ADP ribosylation factor family. It may serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. It increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia.

Specifications

• Antigen: GIT1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS, 9.1mM sodium bicarbonate with 640.91mM DMSO, 136.36mM ethanolamine and no preservative; pH 7.4
• Gene Accession No.: Q68FF6, Q9Y2X7, Q9Z272
• Gene Symbols: GIT1
• Immunogen: Fusion protein amino acids 375-770 (C-terminus) of rat GIT1.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunoprecipitation, Western Blot, Immunocytochemistry
• Clone: N39B/8
• Conjugate: FITC
• Gene: GIT1
• Gene Alias: ARF GAP GIT1; ARF GTPase-activating protein GIT1; CAT1; CAT-1; cool-associated and tyrosine-phosphorylated protein 1; G protein-coupled receptor kinase interacting ArfGAP 1; G protein-coupled receptor kinase interactor 1; G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein; G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein (GIT1); G protein-coupled receptor kinase-interactor 1; GIT ArfGAP 1; Git1; GRK-interacting protein 1; I79_013368; p95Cat
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 216963, 28964, 83709
• Content And Storage: 4°C, store in dark
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov