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  6. Invitrogen™ GITR (TNFRSF18) Recombinant Rabbit Monoclonal Antibody (BLR068G)

Invitrogen™ GITR (TNFRSF18) Recombinant Rabbit Monoclonal Antibody (BLR068G)

Catalog No. PIMA544328
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PIMA544328 10 μL
PIMA544327 100 μL
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Catalog No. PIMA544328 Supplier Invitrogen™ Supplier No. MA544328
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Description

Rabbit Recombinant Monoclonal Antibody

Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE cell sections.

Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), also called GITR or AITR is a protein that in humans is encoded by the TNFRSF18 gene. It is mapped to 1p36.33. This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25 (+)CD4 (+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GITR (TNFRSF18)
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone BLR068G
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation BBS with 0.09% sodium azide; pH 8.2
Gene Tnfrsf18
Gene Accession No. Q9Y5U5
Gene Alias Activation-inducible TNFR family receptor; AITR; CD357; GITR; GITR-D; glucocorticoid-induced TNFR-related protein; PRO364; TNF receptor superfamily activation-inducible protein; TNF receptor superfamily member 18; TNFRSF18; Tumor necrosis factor receptor superfamily member 18; tumor necrosis factor receptor superfamily, member 18; UNQ319; UNQ319/PRO364
Gene Symbols Tnfrsf18
Host Species Rabbit
Immunogen Peptide representing a region between residue 191 and the C-terminus (residue 241) of human Tumor necrosis factor receptor superfamily member 18 (GITR).
Purification Method Purified
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8784
Target Species Human
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG
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