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Invitrogen™ GKN1 Polyclonal Antibody
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Catalog No. PIPA588988
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100 μL
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PIPA588988 100 μL
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Catalog No. PIPA588988 Supplier Invitrogen™ Supplier No. PA588988
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LGVFLAPALA NYNINVNDDN NNAGSGQQSV SVNNEHNVAN VDNNNGWDSW NSIWDYGNGF AATRLFQKKT CIVHKMNKEV MPSIQSLDAL VKEKKLQGKG PGGPPPKGLM YSVNPNKVDD LSKFGKNIAN MCRGIPTYMA EEMQEASLFF YSGTCYTTSV L; Positive Samples: Mouse stomach.

Gastrokine 1, also known as GKN1 and CA11, is a 185 amino acid containing secreted protein belonging to the gastrokine family with a BRICHOS domain and an asn-rich region. GKN1 (also known as an antioncogene) is reported to be down-regulated in human gastric cancer tissue as compared to normal gastric mucosa. Differential display of normal and cancerous gastric tissue suggested that this protein is predominantly expressed in stomach and the expression is down-regulated to considerable frequency in cancer tissue or gastric cancer cell lines examined. This extra cellular protein is co-secreted with mucins and is a signaling growth factor with mitogenic activity and may be involved in maintaining the integrity of the gastric mucosal epithelium.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GKN1
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.87 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene GKN1
Gene Accession No. Q9CR36
Gene Alias 18 kDa antrum mucosa protein; 2200002K21Rik; Amp18; AMP-18; Amp18; gastrokine; BRICD1; BRICHOS domain containing 1; Ca11; FOV; foveolin; gastrokine 1; gastrokine-1; Gkn1; Protein CA11; Protein CA11 homolog; UNQ489/PRO1005
Gene Symbols GKN1
Host Species Rabbit
Immunogen Recombinant protein (or fragment).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 66283
Target Species Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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