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GLCNE Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501989421
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100 μL
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50-198-9421 100 μL
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Catalog No. 50-198-9421 Supplier Bioss Supplier No. BS9882R
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Description

Rabbit Polyclonal Antibody

GNE is a bifunctional enzyme that initiates and regulates the biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. It is a rate-limiting enzyme in the sialic acid biosynthetic pathway. Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes, including cell adhesion and signal transduction. Differential sialylation of cell surface molecules is also implicated in the tumorigenicity and metastatic behavior of malignant cells.

Specifications

Antigen GLCNE
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene GNE
Gene Accession No. Q9Y223
Gene Alias 2310066H07Rik; Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase; DMRV; GLCNE; glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase; GNE; IBM2; ManAc kinase; N-acetylmannosamine kinase; N-acylmannosamine kinase; NM; Uae1; UDP-GlcNAc-2-epimerase; UDP-GlcNAc-2-epimerase/ManAc kinase; UDP-N-acetylglucosamine 2-epimerase (hydrolyzing); UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase; UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase; Uridine diphosphate-N-acetylglucosamine-2-epimerase
Gene Symbols GNE
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human GLCNE.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10020
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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