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Invitrogen™ GLDC Polyclonal Antibody
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Catalog No. PIPA522102
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100 μL
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PIPA522102 100 μL
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Catalog No. PIPA522102 Supplier Invitrogen™ Supplier No. PA522102
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: HePG2. Predicted reactivity: Mouse (91%), Rat (84%), Xenopus laevis (86%), Chicken (85%), Bovine (92%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).
TRUSTED_SUSTAINABILITY

Specifications

Antigen GLDC
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.46 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Gene GLDC
Gene Accession No. P23378, Q91W43
Gene Alias D030049L12Rik; D19Wsu57e; GCE; GCSP; GLDC; Glycine cleavage system P protein; glycine cleavage system protein P; glycine decarboxylase; glycine decarboxylase P-protein; glycine decarboxylase, glycine cleavage system protein P); glycine dehydrogenase (aminomethyl-transferring); glycine dehydrogenase (decarboxylating); glycine dehydrogenase (decarboxylating), mitochondrial; glycine dehydrogenase (decarboxylating; glycine decarboxylase, glycine cleavage system protein P); glycine dehydrogenase [decarboxylating], mitochondrial; HYGN1; RP11-472F14.1
Gene Symbols GLDC
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human Glycine dehydrogenase. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 104174, 2731, 309312
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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