Invitrogen™ GLDC Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA562702

Catalog No. PIPA562702

Description

Immunogen sequence: SCTMKLNSSS ELAPITWKEF ANIHPFVPLD QAQGYQQLFR ELEKDLCELT GYDQVCFQPN SGAQGEYAGL ATIRAYLNQK GEGHRTVCLI PKSAHGTNPA SAHMAGMKIQ PVEVDKYGNI DAVHLKAMVD KHKENL Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 92%.

Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).

Specifications

• Antigen: GLDC
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GLDC
• Gene Alias: D030049L12Rik; D19Wsu57e; GCE; GCSP; GLDC; Glycine cleavage system P protein; glycine cleavage system protein P; glycine decarboxylase; glycine decarboxylase P-protein; glycine decarboxylase, glycine cleavage system protein P); glycine dehydrogenase (aminomethyl-transferring); glycine dehydrogenase (decarboxylating); glycine dehydrogenase (decarboxylating), mitochondrial; glycine dehydrogenase (decarboxylating; glycine decarboxylase, glycine cleavage system protein P); glycine dehydrogenase [decarboxylating], mitochondrial; HYGN1; RP11-472F14.1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2731
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.4 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P23378
• Gene Symbols: GLDC
• Immunogen: Recombinant protein corresponding to Human GLDC. Recombinant protein control fragment (Product #RP-103139).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG