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Invitrogen™ GLDC Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA562702
Description
Immunogen sequence: SCTMKLNSSS ELAPITWKEF ANIHPFVPLD QAQGYQQLFR ELEKDLCELT GYDQVCFQPN SGAQGEYAGL ATIRAYLNQK GEGHRTVCLI PKSAHGTNPA SAHMAGMKIQ PVEVDKYGNI DAVHLKAMVD KHKENL Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 92%.
Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).
Specifications
GLDC | |
Polyclonal | |
Unconjugated | |
GLDC | |
D030049L12Rik; D19Wsu57e; GCE; GCSP; GLDC; Glycine cleavage system P protein; glycine cleavage system protein P; glycine decarboxylase; glycine decarboxylase P-protein; glycine decarboxylase, glycine cleavage system protein P); glycine dehydrogenase (aminomethyl-transferring); glycine dehydrogenase (decarboxylating); glycine dehydrogenase (decarboxylating), mitochondrial; glycine dehydrogenase (decarboxylating; glycine decarboxylase, glycine cleavage system protein P); glycine dehydrogenase [decarboxylating], mitochondrial; HYGN1; RP11-472F14.1 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
2731 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
0.4 mg/mL | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
P23378 | |
GLDC | |
Recombinant protein corresponding to Human GLDC. Recombinant protein control fragment (Product #RP-103139). | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
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