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Invitrogen™ GLDC Polyclonal Antibody
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Catalog No. PIPA597294
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100 μL
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PIPA597294 100 μL
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Catalog No. PIPA597294 Supplier Invitrogen™ Supplier No. PA597294
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Rabbit Polyclonal Antibody

Immunogen sequence: DSSSGGGDSA AAGASRLLER LLPRHDDFAR RHIGPGDKDQ REMLQTLGLA SIDELIEKTV PANIRLKRPL KMEDPVCENE ILATLHAISS KNQIWRSYIG MGYYNCSVPQ TILRNLLENS GWITQYTPYQ PEVSQGRLES LLNYQTMVCD ITGLDMANAS LLDEGTAAAE ALQLCYRHNK RRKFLVDPRC HPQTIAVVQT RAKYTGVLTE LKLPCEMDFS GKDVSGVLFQ YPDTEGKVED FTELVERAHQ SGSLA; Positive Samples: HepG2, DU145; Cellular Location: Mitochondrion.

Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).
TRUSTED_SUSTAINABILITY

Specifications

Antigen GLDC
Applications ELISA, Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.18 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene GLDC
Gene Accession No. P23378, Q91W43
Gene Alias D030049L12Rik; D19Wsu57e; GCE; GCSP; GLDC; Glycine cleavage system P protein; glycine cleavage system protein P; glycine decarboxylase; glycine decarboxylase P-protein; glycine decarboxylase, glycine cleavage system protein P); glycine dehydrogenase (aminomethyl-transferring); glycine dehydrogenase (decarboxylating); glycine dehydrogenase (decarboxylating), mitochondrial; glycine dehydrogenase (decarboxylating; glycine decarboxylase, glycine cleavage system protein P); glycine dehydrogenase [decarboxylating], mitochondrial; HYGN1; RP11-472F14.1
Gene Symbols GLDC
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 36-290 of human GLDC (NP_0001612).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 104174, 2731, 309312
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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