Invitrogen™ GLI1 Monoclonal Antibody (OTI4E2)

Catalog No.	Quantity
PIMA526638	100 μL

Catalog No. PIMA526638

Supplier: Invitrogen™ MA526638

Description

Mouse Monoclonal Antibody

Detects recombinant overexpressed human GLI1, but unfortunately fails to detect the endogenous protein.

This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: GLI1
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: OTI4E2
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: GLI1
• Gene Accession No.: P08151
• Gene Alias: AV235269; GLI; GLI family zinc finger 1; Gli1; GLI-Kruppel family member GLI1; Glioma-associated oncogene; glioma-associated oncogene 1; glioma-associated oncogene homolog; glioma-associated oncogene homolog 1 (zinc finger protein); oncogene GLI; Zfp5; Zfp-5; zinc finger protein 5; zinc finger protein GLI1
• Gene Symbols: GLI1
• Host Species: Mouse
• Immunogen: Human recombinant protein fragment corresponding to amino acids 755-1106 of GLI1 produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2735
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1