GLI2 Monoclonal Antibody (OTI1G2), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA804599

Catalog No. 50-168-0320

Description

Gli-2 belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B.

Specifications

• Antigen: GLI2
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P10070
• Gene Symbols: GLI2
• Immunogen: Human recombit protein fragment corresponding to amino acids 729-1123 of human GLI2 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI1G2
• Conjugate: Unconjugated
• Gene: GLI2
• Gene Alias: CJS, HPE9, PHS2, THP1, THP2
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2736
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid