GLI2 Mouse anti-Human, Clone: OTI1G2, lyophilized, TrueMAB™

Catalog No.	Quantity
50-166-7054	100 μg

Catalog No. 50-166-7054 Supplier OriGene Supplier No. CF804599

Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Gli-2 belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B.

Specifications

• Antigen: GLI2
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI1G2
• Conjugate: Unconjugated
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene: GLI2
• Gene Accession No.: P10070
• Gene Alias: CJS, HPE9, PHS2, THP1, THP2
• Gene Symbols: GLI2
• Host Species: Mouse
• Immunogen: Human recombit protein fragment corresponding to amino acids 729-1123 of human GLI2 produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2736
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG1