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Invitrogen™ GLI2 Polyclonal Antibody
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Catalog No. PA128838
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50 μg
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Catalog No. Quantity
PA128838 50 μg
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Catalog No. PA128838 Supplier Invitrogen™ Supplier No. PA128838
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Description

Rabbit Polyclonal Antibody

PA1-28838 detects Gli2 from mouse samples.

Gli-2 belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GLI2
Applications ELISA, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1.02 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene GLI2
Gene Accession No. P10070, Q0VGT2
Gene Alias AW546128; CJS; GLI family zinc finger 2; GLI family zinc finger protein 2; GLI2; GLI-Kruppel family member GLI2; glioma-associated oncogene family zinc finger 2; HPE9; oncogene GLI2; PHS2; Tax helper protein; tax helper protein 1; tax helper protein 2; tax-responsive element-2 holding protein; tax-responsive element-25-bp sequence binding protein; Thp; THP1; THP2; zinc finger protein GLI2
Gene Symbols GLI2
Host Species Rabbit
Immunogen Synthetic peptide corresponding to amino acids from an internal region of Mouse Gli-2.
Purification Method Antigen affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14633, 2736
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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