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GLI2 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501569915
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50-156-9915 100 μL
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Catalog No. 50-156-9915 Supplier Bethyl Laboratories, Inc Supplier No. A305246A
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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

Gli-2 belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B.

Specifications

Antigen GLI2
Applications Immunoprecipitation
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene GLI2
Gene Accession No. P10070
Gene Alias AW546128
Gene Symbols GLI2
Host Species Rabbit
Immunogen Between 950 and 1000
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2736
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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