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  5. Tocris Bioscience™ Gliocidin

Tocris Bioscience™ Gliocidin
SDP

Catalog No. 889350 Shop All R&D Systems Products
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Catalog No. Quantity
88-935-0 50 mg
88-931-0 10 mg
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Catalog No. 88-935-0 Supplier Tocris Bioscience™ Supplier No. 8893/50
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Description

IMPDH2 (inosine monophosphate dehydrogenase 2) inhibitor, also glioblastoma targeting Nicotinamide mimetic prodrug

Gliocidin is an IMPDH2 (inosine monophosphate dehydrogenase 2) inhibitor. Gliocidin is a nicotinamide-mimetic prodrug that is anabolized into its tumoricidal metabolite, gliocidin-adenine dinucleotide (GAD). Gliocidin kills glioblastoma cells while sparing non-tumour replicative cells. In vivo, Gliocidin penetrates the blood-brain barrier and extends the survival of mice with orthotopic glioblastoma.

Specifications

Chemical Name or Material N-3-Pyridinyl-2-thiophenecarboxamide
CAS 62289-81-0
Quantity 50 mg
Target Dehydrogenase Inhibitors
Molecular Formula C10H8N2OS
Purity 98%
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