GLIS1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA531017

Catalog No. PIPA531017

Description

Recommended positive controls: A549, H1299, MCF-7. Predicted reactivity: Mouse (86%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Glis1 (Gli similar 1) is also known as Gli related Kruppel-like zinc finger 1 and is encoded by the Glis1 gene located on chromosome 1 in humans. It belongs to the Kruppel-like zinc finger family of proteins that constitute mainly of transcription factors and is hence studied for its role in target gene activation and repression, specifically during embryonic development. Glis1 contains five tandem zinc finger motifs, which is the region at which it shares close homology to Glis2 and Glis 3. More recent studies on Glis1 show its interaction with Oct 3/4, Sox2 and KLF4 in efficient generation of iPSC.

Specifications

• Antigen: GLIS1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GLIS1
• Gene Alias: gli homologous protein 1; Gli5; Gli6; GliH1; GLI-Kruppel family member GLI6; GLIS family zinc finger 1; GLIS1; Glis1 Kruppel-like zinc finger protein; GLI-similar 1; translation initiation factor IF-2; zinc finger protein GLIS1; zinc finger transcription factor Gli5
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 148979
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q8NBF1
• Gene Symbols: GLIS1
• Immunogen: Recombinant fragment corresponding to a region within amino acids 227 and 494 of Human GLIS1
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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