Invitrogen™ GLIS3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5102901

Catalog No. PIPA5102901

Description

Antibody detects endogenous levels of total GLIS3.

This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear protein with five C2H2-type zinc finger domains. This protein functions as both a repressor and activator of transcription and is specifically involved in the development of pancreatic beta cells, the thyroid, eye, liver and kidney. Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH). Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only two have been determined.

Specifications

• Antigen: GLIS3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GLIS3
• Gene Alias: 4833409N03Rik; E330013K21Rik; GLIS family zinc finger 3; Glis3; GLI-similar 3; NDH; OK/KNS-cl.4; RGD1565505; Zinc finger protein 515; zinc finger protein GLIS3; ZNF515
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 169792
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q8NEA6
• Gene Symbols: GLIS3
• Immunogen: A synthesized peptide derived from human GLIS3(Accession Q8NEA6), corresponding to amino acid residues A555-V605.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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