Invitrogen™ GLIS3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA530914

Catalog No. PIPA530914

Description

Recommended positive controls: 293T, A431. Predicted reactivity: Mouse (87%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear protein with five C2H2-type zinc finger domains. This protein functions as both a repressor and activator of transcription and is specifically involved in the development of pancreatic beta cells, the thyroid, eye, liver and kidney. Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH). Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only two have been determined.

Specifications

• Antigen: GLIS3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GLIS3
• Gene Alias: 4833409N03Rik; E330013K21Rik; GLIS family zinc finger 3; Glis3; GLI-similar 3; NDH; OK/KNS-cl.4; RGD1565505; Zinc finger protein 515; zinc finger protein GLIS3; ZNF515
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 169792
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.87 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q8NEA6
• Gene Symbols: GLIS3
• Immunogen: Recombinant protein fragment corresponding to a region within amino acids 530 and 730 of Human GLIS3.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG