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Invitrogen™ GLP-1 Monoclonal Antibody (53)
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Catalog No. ABS0445302
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400 μL
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ABS0445302 400 μL
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Catalog No. ABS0445302 Supplier Invitrogen™ Supplier No. ABS0445302
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Description

Mouse Monoclonal Antibody

Specificity: ABS 044-53-02 binds human GLP-1 (9-36) amide. Based on inhibition ELISA, this antibody shows less than 2% cross-Specificity with GLP-1 (7-36) amide. Reactivity: ABS 044-53-02 binds free GLP-1 (9-36) amide in solution. This product has a higher affinity for GLP-1 (9-36) amide than ABS 044-49-02 as determined by an Inhibition assay. NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL.

GCG is also known as GLP1, or Glucagon. Glucagon is a 29-amino acid pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis.It is mapped to 2q36-2q37. GLP1, also known as 7-37 for the codons of the preproglucagon molecule which encode it, renders pancreatic beta-cells 'glucose-competent' and may be useful in the treatment of noninsulin-dependent diabetes mellitus. Also, GLP1 is a potent insulin secretagogue.It plays a major role in the enteroinsular axis, accounting, for example, for the finding that plasma insulin levels accompanying oral intake of glucose are greater than those observed when glucose is given intravenously.
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Specifications

Antigen GLP-1
Applications ELISA, Western Blot
Classification Monoclonal
Clone 53
Concentration 1.15 mg/mL
Conjugate Unconjugated
Formulation PBS with 15mM sodium azide; pH 7.4
Gene GCG
Gene Accession No. P01275
Gene Alias GCG; Glicentin; Glicentin-related polypeptide; GLP1; GLP-1; GLP-1(7-36); GLP-1(7-37); GLP1/2; GLP2; GLP-2; Glu; glucagon; Glucagon like peptide 1; Glucagon-like peptide 1; Glucagon-like peptide 1(7-36); Glucagon-like peptide 1(7-37); Glucagon-like peptide 2; glucagon-like peptide-1; GRPP; Incretin hormone; MGC138331; OXM; OXY; Oxyntomodulin; PPG; preproglucagon
Gene Symbols GCG
Host Species Mouse
Immunogen Synthetic GLP-1(9-18) adsorbed onto aluminum hydroxide gel.
Purification Method Protein A
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2641
Target Species Human
Content And Storage 4°C, store in dark
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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