Invitrogen™ GLRA1 Monoclonal Antibody (7F8E2)

Catalog No.	Quantity
PIMA531740	100 μL

Catalog No. PIMA531740

Supplier: Invitrogen™ MA531740

Description

Mouse Monoclonal Antibody

MA5-31740 has been tested in indirect ELISA.

GLRA1 is a subunit of a pentameric inhibitory glycine receptor, which mediates postsynaptic inhibition in the central nervous system. Defects in GLRA1 are a cause of startle disease (STHE), also known as hereditary hyperekplexia or congenital stiff-person syndrome. Multiple transcript variants encoding different isoforms have been found for GLRA1. Glycine receptors (GlyR) that include GLRA1 are members of the cys-loop family of ligand-gated ion channels, responsible for mediating the inhibitory effects of glycine. GLRA1 are widely distributed throughout the CNS, particularly within the hippocampus, spinal cord and brain stem. Diseases associated with GLRA1 include Hyperekplexia, Hereditary 1 and Hyperekplexia.

Specifications

• Antigen: GLRA1
• Applications: ELISA, Western Blot
• Classification: Monoclonal
• Clone: 7F8E2
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.05% sodium azide
• Gene: GLRA1
• Gene Accession No.: P23415
• Gene Alias: GLRA; Glra1; Glra2; glycine receptor; Glycine receptor 48 kDa subunit; glycine receptor alpha 1; glycine receptor strychnine-binding subunit; Glycine receptor subunit alpha-1; glycine receptor, alpha 1; glycine receptor, alpha 1 subunit; Glyr; GLYRA1; gra1; HKPX1; nmf11; oscillator; ot; spasmodic; spd; STHE
• Gene Symbols: GLRA1
• Host Species: Mouse
• Immunogen: Purified recombinant fragment of human GLRA1 (AA: extra 29-154) expressed in E. coli.
• Purification Method: Protein G
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2741
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1