Invitrogen™ GLRA2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA521673

Catalog No. PIPA521673

Description

Recommended positive controls: 293T, A431, HepG2, mouse brain. Predicted reactivity: Mouse (99%), Rat (99%), Zebrafish (95%), Rhesus Monkey (100%), Bovine (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Glycine is an inhibitory neurotransmitter in the central nervous system. The glycine receptor (GlyR) is a member of the nicotinic acetylcholine receptor of ligand-gated ion channels. This receptor has important roles in a variety of physiological processes, especially in mediating inhibitory neurotransmission in the spinal cord and brain stem. GlyR is a pentameric receptor comprised of alpha and beta subunits. Four alpha-subunits (GLRA1, GLRA2, GLRA3, GLRA4) and one beta-subunit (GLRB) of GlyR have been identified.

Specifications

• Antigen: GLRA2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GLRA2
• Gene Alias: GLR; GLRA2; glycine receptor; glycine receptor alpha 2; glycine receptor alpha 2 subunit; Glycine receptor alpha 2 subunit (glycine receptor, neonatal); glycine receptor strychnine-binding subunit; Glycine receptor subunit alpha-2; glycine receptor, alpha 2; glycine receptor, alpha 2 subunit; glycine receptor, alpha-2 polypeptide; RNNEOGLY
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 237213, 2742
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P23416, Q7TNC8
• Gene Symbols: GLRA2
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 216 of Glycine Receptor alpha 2 (Uniprot ID#P23416).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov