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Invitrogen™ GLRX2 Polyclonal Antibody
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Catalog No. PIPA593087
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100 μL
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PIPA593087 100 μL
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Catalog No. PIPA593087 Supplier Invitrogen™ Supplier No. PA593087
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MESNTSSSLE NLATAPVNQI QETISDNCVV IFSKTSCSYC TMAKKLFHDM NVNYKVVELD LLEYGNQFQD ALYKMTGERT VPRIFVNGTF IGGATDTHRL HKEGKLLPLV HQCYLKKSKR KEFQ; Positive Samples: MCF7; Cellular Location: Mitochondrion, Nucleus.

Glutaredoxin (Grx), also known as thiol transferase, is a small heat-stable oxidoreductase. Grxs form part of the glutaredoxin system, comprising NADPH, GSH and glutathione reductase, which transfers electrons from NADPH to glutaredoxins via GSH. First discovered in E. coli as GSH-dependent hydrogen donors for ribonucleotide reductase, Grx catalyzes GSH-disulfide oxidoreductase via two redox-active cysteine residues. The active sequence (Cys-Pro-Tyr-Cys) is conserved in a variety of species. The 12-kD dithiol protein has a role in reduction of mixed disulfides in cells exposed to oxidative stress.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GLRX2
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.14 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene GLRX2
Gene Accession No. Q9NS18
Gene Alias 1700010P22Rik; AI645710; bA101E13.1 (GRX2 glutaredoxin (thioltransferase) 2); CGI-133; GLRX2; glutaredoxin (thioltransferase) 2; glutaredoxin 2; glutaredoxin 2 (thioltransferase); glutaredoxin-2, mitochondrial; GRX2
Gene Symbols GLRX2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-124 of human GLRX2 (NP_0012303281).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51022
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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