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Invitrogen™ GLRX2 Polyclonal Antibody
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Catalog No. PIPA5115290
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100 μL
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PIPA5115290 100 μL
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Catalog No. PIPA5115290 Supplier Invitrogen™ Supplier No. PA5115290
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total GLRX2.

Glutaredoxin (Grx), also known as thiol transferase, is a small heat-stable oxidoreductase. Grxs form part of the glutaredoxin system, comprising NADPH, GSH and glutathione reductase, which transfers electrons from NADPH to glutaredoxins via GSH. First discovered in E. coli as GSH-dependent hydrogen donors for ribonucleotide reductase, Grx catalyzes GSH-disulfide oxidoreductase via two redox-active cysteine residues. The active sequence (Cys-Pro-Tyr-Cys) is conserved in a variety of species. The 12-kD dithiol protein has a role in reduction of mixed disulfides in cells exposed to oxidative stress.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GLRX2
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene GLRX2
Gene Accession No. Q6AXW1, Q923X4, Q9NS18
Gene Alias 1700010P22Rik; AI645710; bA101E13.1 (GRX2 glutaredoxin (thioltransferase) 2); CGI-133; GLRX2; glutaredoxin (thioltransferase) 2; glutaredoxin 2; glutaredoxin 2 (thioltransferase); glutaredoxin-2, mitochondrial; GRX2
Gene Symbols GLRX2
Host Species Rabbit
Immunogen A synthesized peptide derived from human GLRX2(Accession Q9NS18), corresponding to amino acid residues Y113-F163.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 114022, 51022, 69367
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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