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GLUL/Glutamine Synthetase Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501570129
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Catalog No. Quantity
50-157-0129 10 μL
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Catalog No. 50-157-0129 Supplier Bethyl Laboratories, Inc Supplier No. A305322AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Chicken, Bovine and Dog

Glutamine synthase is part of the glutamine synthetase family. Ammonia incorporation in animals occurs through the actions of glutamate dehydrogenase and glutamine synthase. Glutamate plays the central role in mammalian nitrogen flow, serving as both a nitrogen donor and nitrogen acceptor. It also has an important role in controlling metabolic regulations of neurotransmitter glutamate. Because of the multiple functions and importance of GS in cellular metabolism, both catalytic activities and synthesis are highly regulated. The activity of GS is controlled by adenylylation. Its activity is decreased in the cerebral cortex of brains affected by Alzheimer′s disease, particularly in the vicinity of senile plaques. It is also decreased under conditions of glucose deprivation.

Specifications

Antigen GLUL/Glutamine Synthetase
Applications Immunoprecipitation
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene GLUL
Gene Accession No. P15104
Gene Alias Glutamate-ammonia ligase, GS
Gene Symbols GLUL
Host Species Rabbit
Immunogen Between 275 and 325
Purification Method Antigen affinity chromatography
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2752
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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