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GLUL/Glutamine Synthetase Rabbit anti-Human, Mouse, Polyclonal, Bethyl Laboratories
Rabbit Polyclonal Antibody
Supplier: Bethyl Laboratories, Inc A305323A

Description
The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Rat, Bovine, Dog and Pig
Glutamine synthase is part of the glutamine synthetase family. Ammonia incorporation in animals occurs through the actions of glutamate dehydrogenase and glutamine synthase. Glutamate plays the central role in mammalian nitrogen flow, serving as both a nitrogen donor and nitrogen acceptor. It also has an important role in controlling metabolic regulations of neurotransmitter glutamate. Because of the multiple functions and importance of GS in cellular metabolism, both catalytic activities and synthesis are highly regulated. The activity of GS is controlled by adenylylation. Its activity is decreased in the cerebral cortex of brains affected by Alzheimer′s disease, particularly in the vicinity of senile plaques. It is also decreased under conditions of glucose deprivation.Specifications
GLUL/Glutamine Synthetase | |
Polyclonal | |
Unconjugated | |
GLUL | |
Glutamate-ammonia ligase, GS | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
14645, 2752 | |
4° C | |
Liquid |
Immunoprecipitation, Western Blot | |
1 mg/ml | |
phosphate, tris citrate with 0.09% sodium azide; pH 7-8 | |
P15104, P15105 | |
Glul | |
Between 323 and 373 | |
100 μL | |
Primary | |
Human, Mouse | |
Antibody | |
IgG |
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