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GluR1, GluR2 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501980645
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50-198-0645 100 μL
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Catalog No. 50-198-0645 Supplier Bioss Supplier No. BS10042R
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Description

Rabbit Polyclonal Antibody

GluR1 (glutamate receptor 1) is an ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter, L-glutamate, induces a conformation change that leads to the opening of the cation channel and converts the chemical signal to an electrical impulse. Then, the receptor desensitizes rapidly and enters a transiet inactive state characterized by the presence of a bound agonist. In the presence of CACNG4, CACNG7, or CACNG8 GluR1 shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.

Specifications

Antigen GluR1, GluR2
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene GRIA1
Gene Accession No. P42261
Gene Alias 2900051M01Rik; AI853806; AMPA 1; AMPA glutamate receptor; AMPA-selective glutamate receptor 1; Glr1; Glr-1; GluA1; GLUH 1; GLUH1; GluR K1; GLUR1; GluR-1; GLURA; GluR-A; GluRK1; GluR-K1; glutamate ionotropic receptor AMPA type subunit 1; Glutamate receptor 1; glutamate receptor A; Glutamate receptor ionotropic, AMPA 1; glutamate receptor subunit GluR1; glutamate receptor, ionotropic, AMPA 1; glutamate receptor, ionotropic, AMPA1 (alpha 1); GPRC1A; Gria 1; Gria1; GRM1A; HBGR1; HGBR1; HIPA; HIPA1; MGC13325; MGC133252; mGlu1; MGLUR1; MGLUR1A; NMDA1; NMDAR1; NR1; OTTHUMP00000160643; OTTHUMP00000165781; OTTHUMP00000224241; OTTHUMP00000224242; OTTHUMP00000224243; RP11-350O14.1
Gene Symbols GRIA1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human GluR1.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2890
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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