GluR2 (extracellular) Polyclonal Antibody, Invitrogen™

Guinea Pig Polyclonal Antibody

Supplier:  Thermo Scientific PA5111823

Catalog No. PIPA5111823

Description

Reconstitute antibody with 50 μL of double distilled water (DDW). The reconstituted solution can be stored at 4 degrees C for up to 1 week. For longer periods, small aliquots should be stored at -20 degrees C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min). Peptide sequence is: NVGNINNDKK DETYR(C) Homology: Mouse amino acid residues identical; human - 14/15 amino acid residues identical.

The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by alpha-amino-3-hydroxy-5 -methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct Glutamate Receptor Subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain. The GluR2 subunit is thought to play a key role in forms of synaptic plasticity such as LTD.

Specifications

• Antigen: GluR2 (extracellular)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Gria2
• Gene Alias: AMPA-selective glutamate receptor 2; GluA2; GLUR2; GluR-2; GLURB; GluR-B; GluR-K2; Glutamate receptor 2; Glutamate receptor ionotropic, AMPA 2; GRIA2; HBGR2; OTTHUMP00000165324; OTTHUMP00000220942; OTTHUMP00000220943
• Host Species: Guinea Pig
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14800, 29627
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Immunocytochemistry, Immunofluorescence, Immunomicroscopy, Western Blot
• Concentration: 0.8 mg/mL
• Formulation: PBS with 1% BSA and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P19491, P23819
• Gene Symbols: Gria2
• Immunogen: Peptide corresponding to amino acid residues 179-193 of rat GluR2 (extracellular, N-terminus)
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG